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longevity-public
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6d884964041a57b734af53beb331910b504f0b44
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2 Commits
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SHA1
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claude
6d88496404
Restore lost Tier 4 + Appendix A content (1231 sanitized lines). The original commit pushing SUPPLEMENTS.md to this repo was already missing this content (lost in upstream commit 1afbfe5 which dropped the file from 20,238 → 19,413 lines while adding the Alpha-Lipoic Acid section — the Tier 4 header was preserved but everything below it was truncated). Restored from upstream peak commit 264505c with personal references sanitized: Section 4.1 Statins (stub), Section 4.2 Metformin (full deep dive: Complex I/ND3 inhibition, Konopka 2019 exercise blunting, Aroda 2016 B12 depletion, mGPD inhibition, GI serotonin, TSH suppression, TAME framework interpretation, AMPK alternatives table), Section 4.3 High-Dose Antioxidants (stub), Section 4.4 Rapamycin (stub), Section 4.5 Fluoride (stub), Section 4.6 Iron — Dietary Yes Supplemental No (~254 lines), Section 4.7 GLP-1 Receptor Agonists (~420 lines: STEP/SELECT/SUSTAIN/FLOW trials, lean mass loss, MTC black box, GI pathology, metabolic suppression, TCF7L2 TT pharmacogenomic counterargument), Appendix A Excipients & Additives. Sanitized: 'this user' → 'someone with this profile', 'BMI 19.4 / 58 kg' → 'lean adult / low BMI', 'the user's X genotype' → 'X genotype (in carriers)', 36-year-old male → adult. File now 20,983 lines.
2026-05-10 09:08:04 +08:00
claude
181eb79b49
Add supplements deep-dive compendium — 35 Tier 1-3 sections + 7 Tier 4, covering 9 medicinal mushrooms, mitochondrial supplements, methylation support, metal detoxification agents, and more
2026-05-02 15:30:52 +08:00