claude
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f6ed2d114f
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Add Section 1.6 — Avocado (Whole Fruit and Oil) to DIET.md. Comprehensive deep-dive between Olive Oil and Protein Sources. Hass cultivar dominance noted; lipid profile per 100g flesh and per medium fruit (~67% oleic, ~12% LA = 2.6g LA per fruit, ~6% palmitoleic). PUFA reality check vs marketing claims. Avocado oil adulteration crisis (Wang & Reardon 2020 UC Davis: 82% of commercial samples rancid or adulterated with high-oleic sunflower oil); verified-pure brand list (Marianne's, Bella Vado, CalPure, Olivado, Grove, La Tourangelle), failed brands. Smoke point analysis (refined ~270C, virgin ~190C). Unique bioactives: mannoheptulose (hexokinase inhibitor / CR mimetic in unripe fruit), avocatin B (CPT1 inhibitor, AML selective cytotoxicity, in seed), beta-sitosterol (phytosterol with Helgadottir 2020 phytosterol-CHD caveat), persin (pet toxicity). Micronutrient profile: highest fruit potassium 485mg/100g, B5/folate/copper/K1, lutein+zeaxanthin with Unlu 2005 fat-absorption synergy. Antinutrients: clean overall; latex-fruit syndrome cross-reactivity, tyramine for MAOI/migraine, histamine for MCAS. Glucose handling and framework caveat on postprandial pathologisation. Comparison table vs other fat sources. Environmental/ethical (water use, cartel involvement, deforestation). Practical use, frequency 0.5-1/day. Aligned with caveats verdict. 11 references.
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2026-05-06 10:46:31 +08:00 |
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claude
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eb979a8fa7
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Expand Section 7.3 — Tree Nut Butter Comparison: comprehensive lipid and antinutrient deep-dive. Replaces brief stub with structured comparison covering hazelnut, cashew, almond (full per-nut profiles), plus walnut/pecan/pistachio/Brazil. Lipid profile table for all 5 main nut butters with bis-allylic/peroxidation theory (4-HNE, MDA, isoprostanes, cardiolipin damage cycle). Antinutrient mechanism deep-dives: phytate (IP6 chelation chemistry, mineral binding constants, phytate:zinc ratios, mitigation), oxalate (kidney stones + PDH/Complex II inhibition + Oxalobacter formigenes microbiome interaction), lectins (PNA T-antigen binding), tannins, mycotoxin sources (aflatoxin B1 hepatocarcinogenesis, TP53 R249S signature). Hazelnut: oleic dominance, source-dependent aflatoxin (Turkey vs Italy/Oregon). Cashew: high SFA/stearic mitochondrial fusion benefit, oxalate concern. Almond: borderline-to-avoid analysis (24% PUFA, 469mg/100g oxalate, 140:1 phytate:zinc ratio, LDL-trial framing critique). Final ranking table 1-5 with mitigation strategies for sub-optimal choices. 15 references.
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2026-05-04 18:12:17 +08:00 |
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claude
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181eb79b49
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Add supplements deep-dive compendium — 35 Tier 1-3 sections + 7 Tier 4, covering 9 medicinal mushrooms, mitochondrial supplements, methylation support, metal detoxification agents, and more
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2026-05-02 15:30:52 +08:00 |
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claude
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eb96a3d4e3
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Add therapeutic modalities (PBM, pranayama, yoga, HBOT, fasting)
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2026-05-02 15:30:41 +08:00 |
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claude
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f0c72e1806
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Add diet guide with mechanistic deep dives
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2026-05-02 15:30:40 +08:00 |
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claude
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64b7f8d4cc
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Add PLAN
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2026-05-02 15:30:27 +08:00 |
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claude
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Add ALUMINUM DETOXIFICATION
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2026-05-02 15:30:26 +08:00 |
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claude
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Add MERCURY DETOXIFICATION
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2026-05-02 15:30:25 +08:00 |
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claude
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Add LONGEVITY GUIDELINES
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2026-05-02 15:30:24 +08:00 |
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claude
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d8efce9efb
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Add MULTI LAYER BIOLOGICAL FOUNDATION MODEL
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2026-05-02 15:30:22 +08:00 |
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claude
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1ddea140fd
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Add COMPUTATIONAL BIOLOGY
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2026-05-02 15:30:21 +08:00 |
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claude
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Add METABOLISM AND ALZHEIMERS
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2026-05-02 15:30:20 +08:00 |
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claude
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Add METABOLISM AND CANCER
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2026-05-02 15:30:19 +08:00 |
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claude
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d316ea9b22
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Add METABOLISM AND AGING
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2026-05-02 15:30:18 +08:00 |
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claude
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d900d5ab53
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Add FAT LOSS GUIDE
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2026-05-02 15:30:16 +08:00 |
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claude
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4697dc0c29
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Add exposures and fat loss quick start
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2026-05-02 15:30:05 +08:00 |
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